GRADOLIDE
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Drawn and modelled with RDKit, 3D viewer 3Dmol.js. PubChem CID 5281468
Name
GRADOLIDE
Also reported as
TAROLIDE
IUPAC name
(3S,3aR,4S,6S,6aS,9aS,9bS)-6-hydroxy-3,6,9-trimethyl-2-oxo-2,3,3a,4,5,6,6a,7,9a,9b-decahydroazuleno[4,5-b]furan-3,4-diyl (2Z,2'Z)-bis(2-methylbut-2-enoate)
SMILES
C/C=C(/C)\C(=O)O[C@H]1C[C@]([C@H]2CC=C([C@H]2[C@H]3[C@@H]1[C@](C(=O)O3)(C)OC(=O)/C(=C\C)/C)C)(C)O
Molecular formula
C25H34O7
Molecular weight
446.54 g/mol
Monoisotopic mass
446.2305 Da
Chemical classification: NPClassifier (Kim et al., 2021)
| Plant | Plant part | Amount | Reference |
|---|---|---|---|
| Siler montanum Crantz subsp. montanum | aerial parts | - |
Stefanovic, M., Mladenovic, S., Dermanovic, M., Jeremic, D. (1977). Sesquiterpene lactones from Laserpitium Siler (Umbelliferae). Glas Hem Drus Beograd, 42, 639
|
| Siler montanum Crantz subsp. montanum | fruit | - |
Holub, M., Motl, O., Samek, Z. (1978). The structure and relative and absolute configuration of the sesquiterpenic lactones gradolide and polhovlide from Laserpitium Siler. Collect Czech Chem Commun, 43, 2471 doi:10.1135/cccc19782471
|
| Siler montanum Crantz subsp. montanum | rhizome | - |
Smitalova, Z., Budesinsky, M., Saman, D., Vasickova, S., Holub, M. (1984). Components of the extract from the underground parts of Laserpitium siler L. of slovenian origin, mainly sesquiterpenic lactones. Collect Czech Chem Commun, 49(4), 852-870 doi:10.1135/cccc19840852
|