CHLOROGENIC-ACID
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Drawn and modelled with RDKit, 3D viewer 3Dmol.js. PubChem CID 1794427
Name
CHLOROGENIC-ACID
IUPAC name
(1S,3R,4R,5R)-3-(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexane-1-carboxylic acid
SMILES
C1[C@H]([C@H]([C@@H](C[C@@]1(C(=O)O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O
Molecular formula
C16H18O9
Molecular weight
354.31 g/mol
Monoisotopic mass
354.0951 Da
Pathway:
Superclass:
Class:
Glycoside:
No
Chemical classification: NPClassifier (Kim et al., 2021)
| Plant | Plant part | Amount | Reference |
|---|---|---|---|
| Achillea millefolium L. subsp. millefolium | - | - |
Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
|
| Agrimonia eupatoria L. subsp. eupatoria | leaf | - |
Wealth of India.
|
| Arctium lappa L. | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Arnica montana L. subsp. montana | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Ballota nigra L. subsp. meridionalis (Bég.) Bég. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Betonica officinalis L. | - | - |
CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
|
| Betonica officinalis L. | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Chondrilla juncea L. | leaf | - |
Terencio, M.C., Giner, R.M., Sanz, M.J., Manez, S., Rios, J.L. (1993). On the occurrence of caffeoyltartronic acid and other phenolics in Chondrilla juncea. Z Naturforsch Ser C, 48(5/6), 417-419 doi:10.1515/znc-1993-5-603
|
| Cichorium intybus L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Cichorium intybus L. | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Cichorium intybus L. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Cichorium intybus L. | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Clematis vitalba L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Crataegus monogyna Jacq. | - | - |
Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133.
|
| Cuscuta campestris Yunck. | aerial parts | - |
Loffler, C., Czygan, F.C., Proksch, P. (1997). Phenolic constituents as taxonomic markers in the genus Cuscuta (Cuscutaceae). Biochem Syst Ecol, 25(4), 297-303 doi:10.1016/s0305-1978(97)00015-x
|
| Dactylis glomerata L. subsp. glomerata | aerial parts | - |
Mino, Y., Yamaguchi, M. (1976). Bound-type chlorogenic acid in the stubble of orchardgrass (Dactylis glomerata L.). Nippon Sochi Gakkaishi, 22(4), 289-292
|
| Daucus carota L. | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Dipsacus fullonum L. | - | - |
List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
|
| Equisetum arvense L. | aerial parts | - |
Jim Duke's personal files.
|
| Eryngium campestre L. | aerial parts | - |
Hohmann, J., Pall, Z., Gunther, G., Mathe, I. (1997). Flavonolacyl glycosides of the aerial parts of Eryngium campestre. Planta Med, 63(1), 96 doi:10.1055/s-2006-957620
|
| Eupatorium cannabinum L. subsp. cannabinum | aerial parts | - |
Oswiecimska, M., Sendra, J. (1972). Eupatorium cannabinum L. Search for biologically active fraction. Diss Pharm Pharmacol, 24, 475-483
|
| Eupatorium cannabinum L. subsp. cannabinum | flower | - |
Pagani, F., Romussi, G. (1967). On the constituents of Eupatorium cannabinum L. var. syriacum (Jacq.). Farmaco Ed Prat, 22, 771-785
|
| Eupatorium cannabinum L. subsp. cannabinum | stem | - |
Pagani, F., Romussi, G. (1967). On the constituents of Eupatorium cannabinum L. var. syriacum (Jacq.). Farmaco Ed Prat, 22, 771-785
|
| Euphorbia helioscopia L. subsp. helioscopia | aerial parts | - |
Ahn, B.T., Lee, S.H., Ro, J.S., Lee, K.S. (1995). A chemotaxonomic study on Euphorbiaceae in Korea. Nat Prod Sci, 1(1), 86-98
|
| Euphorbia maculata L. | aerial parts | - |
Ahn, B.T., Lee, S.H., Ro, J.S., Lee, K.S. (1995). A chemotaxonomic study on Euphorbiaceae in Korea. Nat Prod Sci, 1(1), 86-98
|
| Fagus sylvatica L. | leaf | - |
Wojciechowska, B., Kocik, H., Zajac, K., Niemtur, S. (1984). Content of chlorogenic acid in Fagus sylvatica leaves. Pr Nauk Uniw Slask Katowicach, 16, 129-136
|
| Fumaria officinalis L. subsp. officinalis | - | - |
Massa, V., Susplugas, P., Anelli, A. (1971). Phenolic pigments of Fumaria officinalis. Trav Soc Pharm(Montpellier), 31(3), 233-236
|
| Galium aparine L. | aerial parts | - |
Tzakou, O., Verykokidou, E., Harvala, C. (1994). Comparative hplc analysis of polyphenolic compounds in four species of Galium L. J Liq Chromatogr, 17(20), 4463-4467 doi:10.1080/10826079408013630
|
| Galium aparine L. | fruit | - |
Seabra, R.M., Silveira, J.A., Vasconcelos, M.H. (1993). Phenolic compounds from Galium aparine and G. broteroanm. Plant Med Phytother, 26(1), 49-51
|
| Galium mollugo L. | rhizome | - |
Shapiro, D.K., Kudinov, M.A., Biryukova, L.G., Narizhnaya, T.L., Anikhimovskaya, L.V. (1985). Evaluation of the chemical composition of some Galium species growing in the bssr as potential (raw material sources). Vestsi Akad Navuk Bssr Ser Biyal Navuk, (4), 24-28
|
| Geranium purpureum Vill. | flower | - |
(1)In vitro anti-urease, antioxidant activities and phytochemical composition of Geranium purpureum - (2)Antimicrobial Activity and Analyses of Six Geranium L. Species with Headspace SPME and Hydrodistillation
|
| Glechoma hederacea L. | - | - |
Vadmecum Garcia, A.A., et al. 1998. Fitoterapia Vademecum de Prescripcioon. Masson, S. A. Barcelona, Espana. 1148 pp.
|
| Hedera helix L. subsp. helix | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Helminthotheca echioides (L.) Holub | aerial parts | - |
Giner, R.M., Recio, M.C., Cuellar, M.J., Manez, S., Peris, J.B., Stubing, G., Mateu, I., Rios, J.L. (1993). A taxonomical study of the subtribe leontodontinae based on the distribution of phenolic compounds. Biochem Syst Ecol, 21(5), 613-616 doi:10.1016/0305-1978(93)90061-u
|
| Humulus lupulus L. | fruit | - |
List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
|
| Hypericum perforatum L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Hypericum perforatum L. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Juglans regia L. | seed | 10-28 ppm; 220-800 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Juniperus communis L. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Lapsana communis L. subsp. communis | aerial parts | - |
Fontanel, D., Galtier, C., Ciel, C., Gueiffier, A. (1998). Caffeoyl quinic and tartaric acids and flavonoids from Lapsana communis L. subsp. communis (Asteraceae). Z Naturforsch Ser C, 53(11/12), 1090-1092 doi:10.1515/znc-1998-11-1224
|
| Laserpitium latifolium L. | leaf | - |
Vereskovskii, V.V., Kuznetsova, Z.P., Loznukho, I.V., Sokolov, I.V., Osokin, D.M. (1993). Phenolic compounds of Laserpitium latifolium. Chem Nat Comp, 28(6), 631-632 doi:10.1007/bf00630451
|
| Lonicera japonica Thunb. | flower | 445-60000 ppm |
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
|
| Lythrum salicaria L. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Matricaria chamomilla L. | - | - |
Oliveira, L.J., Pintoneto, N., Tavares, M.F.M. (2001). Critical assessment of electrolyte systems for the capillary electrophoresis analysis of phenolic compounds in herbal extracts. J Microcol Sep, 13(6), 227-235 doi:10.1002/mcs.1047
|
| Matricaria chamomilla L. | flower | - |
Wang, Y., Tang, H., Nicholson, J.K., Hylands, P.J., Sampson, J., Whitcombe, I., Stewart, C.G., Caiger, S., Oru, I., Holmes, E. (2004). Metabolomic strategy for the classification and quality control of phytomedicine: a case study of chamomile flower (Matricaria recutita L.). Planta Med, 70(3), 250-255 doi:10.1055/s-2004-815543
|
| Morus alba L. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Onopordum acanthium L. subsp. acanthium | flower | - |
Karl, C., Mueller, G., Pedersen, P.A. (1976). On the phytochemistry of the flowers of Onopordon acanthium L. (cotton thistle). Dtsch Apoth Ztg, 116, 57-59
|
| Onopordum acanthium L. subsp. acanthium | flower | - |
Karl, C., Muller, G., Pedersen, P.A. (1976). Zur phytochemie der bluten von Onopordon acanthium L.(eselsdistel). Dtsch Apoth Ztg, 116, 57
|
| Pentanema salicinum (L.) D.Gut.Larr., Santos-Vicente, Anderb., E.Rico & M.M.Mart.Ort. | leaf | - |
Shiroya, M., Hattori, S. (1955). Studies on the browning and blackening of plant tissues. iii. occurrence in the leaves of dahlia and several other plants of chlorogenic acid as the principal browning agent. Physiol Plant, 8, 358-369 doi:10.1111/j.1399-3054.1955.tb08981.x
|
| Plantago lanceolata L. | leaf | - |
Maksyutina, N.P. (1971). Hydroxycinnamic acids from Plantago major and Plantago lanceolata. Khim Prir Soedin, 7(6), 824-825 doi:10.1007/bf00567943
|
| Plantago major L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Populus alba L. | bark | - |
Klimczak, M., Kahl, W., Grodzinska-zachewieja, Z. (1972). Studies on phenolic acids, derivatives of cinnamic acid, in plants. Diss Pharm Pharmacol, 24(2), 181-184
|
| Populus alba L. | bud | - |
Klimczak, M., Kahl, W., Grodzinska-zachewieja, Z. (1972). Studies on phenolic acids, derivatives of cinnamic acid, in plants. Diss Pharm Pharmacol, 24(2), 181-184
|
| Populus tremula L. | bark | - |
Klimczak, M., Kahl, W., Grodzinska-zachewieja, Z. (1972). Studies on phenolic acids, derivatives of cinnamic acid, in plants. Diss Pharm Pharmacol, 24(2), 181-184
|
| Populus tremula L. | bud | - |
Klimczak, M., Kahl, W., Grodzinska-zachewieja, Z. (1972). Studies on phenolic acids, derivatives of cinnamic acid, in plants. Diss Pharm Pharmacol, 24(2), 181-184
|
| Prunus persica (L.) Batsch | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Prunus persica (L.) Batsch | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Pyrus communis L. subsp. pyraster (L.) Ehrh. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Sambucus ebulus L. | aerial parts | - |
Yesilada, E. (1997). Evaluation of the anti-inflammatory activity of the turkish medicinal plant Sambucus ebulus. Chem Nat Comp, 33(5), 539-540 doi:10.1007/bf02254798
|
| Sambucus ebulus L. | fruit | - |
Chiarlo, B., Cajelli, E., Piazzai, G. (1978). Some constituents of the drupes of Sambucus ebulus. I. anthocyanin pigments and phenolic acids. Fitoterapia, 49, 99
|
| Sambucus nigra L. | flower | 26000 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Solidago virgaurea L. subsp. virgaurea | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Stellaria media (L.) Vill. | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Succisa pratensis Moench | - | - |
Kowalczyk, A., Krzyanowska, J. (1999). Preliminary antifungal activity of some Dipsacaceae family plants. Herba Pol, 45(2), 101-107
|
| Symphytum officinale L. | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Tanacetum vulgare L. subsp. vulgare | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Taraxacum F.H.Wigg. sect. Taraxacum | - | - |
Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
|
| Teucrium chamaedrys L. subsp. chamaedrys | - | 200 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Trifolium pratense L. subsp. pratense | - | - |
J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
|
| Triticum aestivum L. subsp. aestivum | seed | 5 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Urtica dioica L. | - | 200-5000 ppm |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
|
| Urtica dioica L. | aerial parts | - |
Jim Duke's personal files.
|
| Urtica dioica L. | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Urtica dioica L. | leaf | - |
Jim Duke's personal files.
|
| Vaccinium myrtillus L. | fruit | 1900 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Vaccinium myrtillus L. | leaf | 2800 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|