CAFFEIC-ACID
Drag to rotate, scroll to zoom
Drawn and modelled with RDKit, 3D viewer 3Dmol.js. PubChem CID 689043
Name
CAFFEIC-ACID
Also reported as
TRANS-CAFFEIC-ACID
IUPAC name
(E)-3-(3,4-dihydroxyphenyl)acrylic acid
SMILES
C1=CC(=C(C=C1/C=C/C(=O)O)O)O
Molecular formula
C9H8O4
Molecular weight
180.16 g/mol
Monoisotopic mass
180.0423 Da
Pathway:
Superclass:
Class:
Glycoside:
No
Chemical classification: NPClassifier (Kim et al., 2021)
| Plant | Plant part | Amount | Reference |
|---|---|---|---|
| Achillea millefolium L. subsp. millefolium | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Agrimonia eupatoria L. subsp. eupatoria | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Alchemilla glaucescens Wallr. | aerial parts | - |
Sokoloswka-wozniak, A. (1997). Phenolic acids in some species of the genus Alchemilla L. Herba Pol, 43(4), 388-392
|
| Althaea cannabina L. | flower | - |
Gudej, J., Bieganowska, M.L. (1990). Chromatographic investigation of phenolic acids and coumarins in the leaves and flowers of some species of the genus Althaea. J Liq Chromatogr, 13(20), 4081-4092 doi:10.1080/01483919008049590
|
| Althaea cannabina L. | leaf | - |
Gudej, J., Bieganowska, M.L. (1990). Chromatographic investigation of phenolic acids and coumarins in the leaves and flowers of some species of the genus Althaea. J Liq Chromatogr, 13(20), 4081-4092 doi:10.1080/01483919008049590
|
| Anacamptis morio (L.) R.M.Bateman, Pridgeon & M.W.Chase | flower | - |
Pagani, F. (1976). Phytoconstituents of Orchidaceae. part 1. components of Orchis sambucina and Orchis morio. Boll Chim Farm, 115, 407
|
| Arctium lappa L. | root | 2500 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Arnica montana L. subsp. montana | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Ballota nigra L. subsp. meridionalis (Bég.) Bég. | leaf | 2000 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Bellis perennis L. | flower | - |
Grabias, B., Dombrowicz, E., Kalemba, D., Swiatek, L. (1995). Phenolic acids in flores bellidis and herba tropaeoli. Herba Pol, 41(3), 111-114
|
| Betonica officinalis L. | - | 5000 ppm |
CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
|
| Betonica officinalis L. | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Campanula rotundifolia L. subsp. rotundifolia | aerial parts | - |
Teslov, L.S., Koretskaya, L.N., Tsareva, G.I. (1983). Phenolic compounds of Campanula rotundifolia and C. persicifolia. Chem Nat Comp, 19(3), 367 doi:10.1007/bf00579785
|
| Castanea sativa Mill. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Chondrilla juncea L. | leaf | - |
Terencio, M.C., Giner, R.M., Sanz, M.J., Manez, S., Rios, J.L. (1993). On the occurrence of caffeoyltartronic acid and other phenolics in Chondrilla juncea. Z Naturforsch Ser C, 48(5/6), 417-419 doi:10.1515/znc-1993-5-603
|
| Cichorium intybus L. | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Cichorium intybus L. | leaf | 767 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Cirsium vulgare (Savi) Ten. subsp. vulgare | leaf | - |
Mcgowan, S.G., Wallace, J.W. (1972). Flavonoids and phenolic acids from Cirsium lanceolatum. Phytochemistry, 11, 1503-1504 doi:10.1016/s0031-9422(00)90119-5
|
| Clematis vitalba L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Convolvulus arvensis L. | aerial parts | - |
Provost, C. (1959). Paper chromatography of flavonoids of Convolvulus arvensis. Bull Soc Hist Nat Doubs, 62(3), 67
|
| Cota tinctoria (L.) J.Gay subsp. australis (R.Fern.) Oberpr. & Greuter | flower | - |
Masterova, I., Grancaiova, Z., Suchy, V., Grancai, D., Ubik, K. (1993). Phenolic substances in flowers of Anthemis tinctoria. Fitoterapia, 64(3), 277
|
| Crataegus monogyna Jacq. | - | - |
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
|
| Daucus carota L. | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Dipsacus fullonum L. | - | - |
List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
|
| Equisetum arvense L. | - | 8000 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Equisetum arvense L. | aerial parts | - |
Jim Duke's personal files.
|
| Erigeron canadensis L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Eryngium campestre L. | aerial parts | - |
Hohmann, J., Pall, Z., Gunther, G., Mathe, I. (1997). Flavonolacyl glycosides of the aerial parts of Eryngium campestre. Planta Med, 63(1), 96 doi:10.1055/s-2006-957620
|
| Eupatorium cannabinum L. subsp. cannabinum | aerial parts | - |
Oswiecimska, M., Sendra, J. (1972). Eupatorium cannabinum L. Search for biologically active fraction. Diss Pharm Pharmacol, 24, 475-483
|
| Eupatorium cannabinum L. subsp. cannabinum | flower | - |
Pagani, F., Romussi, G. (1967). On the constituents of Eupatorium cannabinum L. var. syriacum (Jacq.). Farmaco Ed Prat, 22, 771-785
|
| Eupatorium cannabinum L. subsp. cannabinum | stem | - |
Pagani, F., Romussi, G. (1967). On the constituents of Eupatorium cannabinum L. var. syriacum (Jacq.). Farmaco Ed Prat, 22, 771-785
|
| Fumaria officinalis L. subsp. officinalis | - | - |
Sousek, J., Guedon, D., Adam, T., Bochorakova, H., Taborska, E., Valka, I., Simanek, V. (1999). Alkaloids and organic acids content of eight Fumaria species. Phytochem Anal, 10(1), 6-11 doi:10.1002/(sici)1099-1565(199901/02)10:1
|
| Gentiana lutea L. subsp. lutea | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Geranium purpureum Vill. | - | - |
(1)In vitro anti-urease, antioxidant activities and phytochemical composition of Geranium purpureum - (2)Antimicrobial Activity and Analyses of Six Geranium L. Species with Headspace SPME and Hydrodistillation
|
| Geranium pusillum L. | aerial parts | - |
Kobakhidze, K.B., Alaniya, M.D. (2001). Phenolic acids of Geranium pusillum. Chem Nat Comp, 37(6), 571-572 doi:10.1023/a:1014885303700
|
| Glechoma hederacea L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Humulus lupulus L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Hypericum perforatum L. | - | 1000 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Hypericum perforatum L. | aerial parts | 1000 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Juglans regia L. | leaf | - |
List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
|
| Juglans regia L. | seed | 1-6 ppm; 15-115 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Juniperus communis L. | fruit | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Juniperus communis L. | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Lapsana communis L. subsp. communis | aerial parts | - |
Fontanel, D., Galtier, C., Ciel, C., Gueiffier, A. (1998). Caffeoyl quinic and tartaric acids and flavonoids from Lapsana communis L. subsp. communis (Asteraceae). Z Naturforsch Ser C, 53(11/12), 1090-1092 doi:10.1515/znc-1998-11-1224
|
| Linaria vulgaris Mill. subsp. vulgaris | aerial parts | - |
Sokolowska-wozniak, A., Szewczyk, K., Nowak, R. (2003). Phenolic acids from the herb of Linaria vulgaris (L.) Mill. Herba Pol, 49(3/4), 161-165
|
| Lolium arundinaceum (Schreb.) Darbysh. subsp. arundinaceum | leaf | - |
Buta, J.G., Spaulding, D.W. (1989). Allelochemicals in tall fescue-abscisic and phenolic acids. J Chem Ecol, 15(5), 1629-1636 doi:10.1007/bf01012389
|
| Lolium arundinaceum (Schreb.) Darbysh. subsp. arundinaceum | seed | - |
Klejdus, B., Kuban, V. (2000). High performance liquid chromatographic determination of phenolic compounds in seed exudates of Festuca arundinacea and F. pratense. Phytochem Anal, 11(6), 357-379 doi:10.1002/1099-1565(200011/12)11:6
|
| Lolium multiflorum Lam. | aerial parts | - |
Naqvi, H.H. (1976). Some phytotoxic compounds in italian ryegrass. Pak J Bot, 8, 63
|
| Matricaria chamomilla L. | - | - |
Oliveira, L.J., Pintoneto, N., Tavares, M.F.M. (2001). Critical assessment of electrolyte systems for the capillary electrophoresis analysis of phenolic compounds in herbal extracts. J Microcol Sep, 13(6), 227-235 doi:10.1002/mcs.1047
|
| Matricaria chamomilla L. | flower | - |
Reichling, J., Becker, H., Exner, J., Draeger, P.D. (1979). Comparative studies of various commercial samples of Matricaria flowers. essential oil, flavonoids, coumarins, phenolic acids and plant protectant residues. Pharm-Ztg, 124, 1998-2005
|
| Medicago sativa L. | cell culture | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Morus alba L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Onopordum acanthium L. subsp. acanthium | flower | - |
Karl, C., Mueller, G., Pedersen, P.A. (1976). On the phytochemistry of the flowers of Onopordon acanthium L. (cotton thistle). Dtsch Apoth Ztg, 116, 57-59
|
| Onopordum acanthium L. subsp. acanthium | flower | - |
Karl, C., Muller, G., Pedersen, P.A. (1976). Zur phytochemie der bluten von Onopordon acanthium L.(eselsdistel). Dtsch Apoth Ztg, 116, 57
|
| Pentanema salicinum (L.) D.Gut.Larr., Santos-Vicente, Anderb., E.Rico & M.M.Mart.Ort. | leaf | - |
Shiroya, M., Hattori, S. (1955). Studies on the browning and blackening of plant tissues. iii. occurrence in the leaves of dahlia and several other plants of chlorogenic acid as the principal browning agent. Physiol Plant, 8, 358-369 doi:10.1111/j.1399-3054.1955.tb08981.x
|
| Persicaria lapathifolia (L.) Delarbre subsp. lapathifolia | aerial parts | - |
Smolarz, H.D. (2000). Chromatographical analysis of phenolic acids in some species of Polygonum L. genus. part 2. quantitative determination of the major components by high performance liquid chromatography (hplc). Acta Soc Bot Pol, 69(1), 21-23
|
| Persicaria maculosa Gray | aerial parts | - |
Smolarz, H.D. (2000). Chromatographical analysis of phenolic acids in some species of Polygonum L. genus. part 2. quantitative determination of the major components by high performance liquid chromatography (hplc). Acta Soc Bot Pol, 69(1), 21-23
|
| Persicaria mitis (Schrank) Assenov | aerial parts | - |
Smolarz, H.D. (2000). Chromatographical analysis of phenolic acids in some species of Polygonum L. genus. part 2. quantitative determination of the major components by high performance liquid chromatography (hplc). Acta Soc Bot Pol, 69(1), 21-23
|
| Plantago major L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Populus alba L. | bud | - |
Klimczak, M., Kahl, W., Grodzinska-zachewieja, Z. (1972). Studies on phenolic acids, derivatives of cinnamic acid, in plants. Diss Pharm Pharmacol, 24(2), 181-184
|
| Populus tremula L. | bud | - |
Klimczak, M., Kahl, W., Grodzinska-zachewieja, Z. (1972). Studies on phenolic acids, derivatives of cinnamic acid, in plants. Diss Pharm Pharmacol, 24(2), 181-184
|
| Portulaca oleracea L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Poterium sanguisorba L. subsp. balearicum (Bourg. ex Nyman) Stace | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Poterium sanguisorba L. subsp. sanguisorba | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Prunella grandiflora (L.) Scholler | - | - |
List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
|
| Prunella vulgaris L. subsp. vulgaris | - | - |
List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
|
| Prunus persica (L.) Batsch | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Prunus spinosa L. subsp. spinosa | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Pteridium aquilinum (L.) Kuhn subsp. aquilinum | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Pyrus communis L. subsp. pyraster (L.) Ehrh. | fruit | 43-19700 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Rosa canina L. | cell culture | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Rosa canina L. | stem | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Rubus idaeus L. subsp. idaeus | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Rubus idaeus L. subsp. idaeus | fruit | - |
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
|
| Salvia glutinosa L. | seed | 306 ppm |
Phenolic Compounds in Food and Their Effects on Health, 67.
|
| Salvia pratensis L. | seed | 306 ppm |
Phenolic Compounds in Food and Their Effects on Health, 67.
|
| Sambucus ebulus L. | fruit | - |
Chiarlo, B., Cajelli, E., Piazzai, G. (1978). Constituents of the drupes of Sambucus ebulus. I. anthocyanin pigments and phenolic acids. Fitoterapia, 49(3), 99-101
|
| Sambucus ebulus L. | fruit | - |
Chiarlo, B., Cajelli, E., Piazzai, G. (1978). Some constituents of the drupes of Sambucus ebulus. I. anthocyanin pigments and phenolic acids. Fitoterapia, 49, 99
|
| Sambucus nigra L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Scrophularia nodosa L. | seed | - |
Grabia, B., Kurowska, A., Swiatek, L. (1995). Chemical composition of Scropularia nodosa L. seeds. Herba Pol, 41(2), 59-63
|
| Senecio vulgaris L. subsp. vulgaris | - | - |
Ferry, S. (1977). Polyphenols (phenolic acids,flavonoids) of some indigenous groundsels. Plant Med Phytother, 11, 25-39
|
| Solidago gigantea Aiton | - | 21980 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Solidago virgaurea L. subsp. virgaurea | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Spartium junceum L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Stellaria media (L.) Vill. | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Symphytum officinale L. | root | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Tanacetum vulgare L. subsp. vulgare | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Taraxacum F.H.Wigg. sect. Taraxacum | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Taraxacum F.H.Wigg. sect. Taraxacum | flower | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Teucrium chamaedrys L. subsp. chamaedrys | - | - |
U.S. Department of Agriculture, Agricultural Research Service. Dr. Duke's Phytochemical and Ethnobotanical Databases. https://phytochem.nal.usda.gov/
|
| Trifolium pratense L. subsp. pratense | flower | - |
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
|
| Trifolium pratense L. subsp. pratense | leaf | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Trigonella officinalis (L.) Coulot & Rabaute | - | - |
Pharmazie, 46: 156, 1991.
|
| Trigonella officinalis (L.) Coulot & Rabaute | aerial parts | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Triticum aestivum L. subsp. aestivum | seed | 3-4 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Urtica dioica L. | - | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Urtica dioica L. | leaf | - |
Jim Duke's personal files.
|
| Vaccinium myrtillus L. | fruit | - |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Vaccinium myrtillus L. | leaf | 40 ppm |
Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
|
| Verbascum phlomoides L. | flower | - |
Osvath, K., Papay, V., Toth, L. (1982). Constituents of the flowers of Verbascum phlomoides L. and their therapeutical application. Herba Hung, 21(2/3), 141-147
|
| Veronica chamaedrys L. subsp. chamaedrys | aerial parts | - |
Swiatek, L., Broda, B., Frej, E. (1971). Chemical composition of Veronica chamaedrys herb. Acta Pol Pharm, 28, 189-194
|